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Microorganisms

Microorganisms — Friend and Foe

What you'll learn

  • What microorganisms are and their main types.
  • How microorganisms are useful to humans.
  • How microorganisms cause disease (pathogens).
  • Food preservation methods to prevent microbial spoilage.
  • Antibiotics and vaccines — how they work.

Key concepts

What are microorganisms?

  • Microorganisms (microbes): living organisms too small to be seen with the naked eye; require a microscope.
  • Found everywhere: soil, water, air, inside our bodies, in extreme environments (hot springs, ice caps).
  • First observed by Antonie van Leeuwenhoek (1670s) using his hand-made microscope.

Major types of microorganisms

TypeFeaturesExamples
BacteriaSingle-celled; prokaryote (no nucleus); found in soil, water, air, bodyLactobacillus (curd), Rhizobium (legume roots), Vibrio cholerae (cholera)
FungiEukaryote; not plants; decomposers; some multicellularAspergillus (bread mould), Penicillium (antibiotic), yeast (Saccharomyces)
ProtozoaSingle-celled; eukaryote; most live in water or as parasitesPlasmodium (malaria), Amoeba, Paramecium
AlgaeMostly aquatic; photosynthetic; range from single-cell to large seaweedChlamydomonas, Spirogyra, Ulva (sea lettuce)
VirusesNOT truly living (no cells, no metabolism alone); need a host cell to reproduceInfluenza, COVID-19 (SARS-CoV-2), Polio, HIV, Measles
  • Virus vs Bacteria: Viruses are much smaller; antibiotics don't work on viruses; viruses use host cell machinery to replicate.

Microorganisms as friends — useful roles

In food production

ProductMicroorganismHow
Curd (yoghurt)Lactobacillus bacteriaFerments lactose in milk → lactic acid → milk curdles
Bread / Idli / DosaYeast (Saccharomyces cerevisiae)Ferments sugars → CO₂ gas → dough rises
CheeseVarious bacteria + fungi (Penicillium in blue cheese)Fermentation changes milk proteins and fats
VinegarAcetobacter bacteriaOxidises alcohol → acetic acid
Alcohol (beer, wine)YeastFerments sugar → ethanol + CO₂
Idli/Dosa batterLactic acid bacteria + yeastNatural fermentation; also increases nutritional value

In medicine

  • Antibiotics: chemicals produced by microorganisms (usually fungi) that kill or inhibit bacteria.
    • Penicillin: discovered by Alexander Fleming (1928) from Penicillium mould; revolutionised medicine.
    • Other antibiotics: streptomycin, tetracycline, erythromycin.
    • Important: antibiotics work on bacteria, NOT on viruses (don't take antibiotics for a cold/flu!).
    • Antibiotic resistance: overuse leads to resistant "superbugs" — global health crisis.
  • Vaccines: use killed/weakened pathogens to train immune system.
    • Edward Jenner (1796): first vaccine — cowpox to protect against smallpox.
    • Louis Pasteur: germ theory; developed vaccines for cholera, anthrax, rabies.
    • India's vaccines: OPV (polio), BCG (TB), MMR (measles-mumps-rubella), COVID-19 vaccines (Covaxin, Covishield).

In agriculture

  • Biological nitrogen fixation: Rhizobium bacteria in legume root nodules convert atmospheric N₂ to usable ammonia → reduces need for chemical fertilisers.
  • Biofertilisers: blue-green algae (Cyanobacteria) fix nitrogen in paddy fields.
  • Decomposers: fungi and bacteria break down dead organic matter → nutrients return to soil → supports plant growth.
  • Biopesticides: Bacillus thuringiensis (Bt) produces toxins that kill specific insect pests; used instead of harmful chemical pesticides.

In the environment

  • Decomposition: microorganisms break down dead plants, animals, and waste → recycle carbon, nitrogen, phosphorus.
  • Sewage treatment: bacteria break down organic waste in sewage treatment plants.
  • Bioremediation: certain bacteria can break down oil spills and toxic chemicals.

Microorganisms as foes — diseases they cause

Diseases caused by bacteria

DiseaseBacteriumSpreadSymptoms
Tuberculosis (TB)Mycobacterium tuberculosisAir (droplets)Cough, fever, weight loss
CholeraVibrio choleraeContaminated water/foodSevere diarrhoea, dehydration
TyphoidSalmonella typhiContaminated water/foodHigh fever, stomach pain
Food poisoningStaphylococcus, SalmonellaInfected foodVomiting, diarrhoea
AnthraxBacillus anthracisInfected animals/soilSkin sores; can be fatal

Diseases caused by viruses

DiseaseVirusSpread
Common cold / FluRhinovirus / InfluenzaAir droplets
COVID-19SARS-CoV-2Air droplets, surfaces
PolioPoliovirusContaminated water/faeces
MeaslesMeasles virusAir droplets
DengueDengue virusAedes mosquito bite
HIV / AIDSHIVBlood, sexual contact, mother-to-child
Hepatitis BHepatitis B virusBlood, sexual contact

Diseases caused by protozoa

DiseaseProtozoanVector
MalariaPlasmodium falciparum/vivaxAnopheles female mosquito
Kala-azar (Leishmaniasis)LeishmaniaSandfly
Dysentery (Amoebic)Entamoeba histolyticaContaminated water/food

Diseases caused by fungi

  • Ringworm: fungal infection of skin; circular red rash (NOT a worm).
  • Athlete's foot: Tinea pedis; affects skin between toes.
  • Candidiasis: Candida albicans; mouth, gut, or vaginal infection (especially in immunocompromised people).

Food preservation — keeping microorganisms away

MethodPrincipleExamples
Heating / PasteurisationHigh temp kills microbesMilk (72°C for 15s); canned food
RefrigerationLow temp slows microbial growthMeat, dairy, vegetables
Deep freezingVery low temp stops microbial growthFrozen food; long storage
SaltingSalt draws water out of food (osmosis); microbes dehydratePickles, salted fish, cured meat
SugarSimilar to salt; high sugar concentration draws water outJams, jellies, mithai
Drying / DehydrationRemoves water; no water → no microbial growthDried fruits, papad, spices
Vinegar (acidification)Acidic pH inhibits most bacteriaPickles, chutneys
Chemical preservativesSodium benzoate, potassium sorbate added to foodPackaged juices, sauces
Vacuum packingRemove oxygen; aerobic bacteria can't growPackaged meats, chips

Pasteurisation

  • Process developed by Louis Pasteur (1850s).
  • Heat liquid (milk) to ~72°C for 15 seconds → kills harmful pathogens without changing taste significantly.
  • Then rapidly cool to < 4°C.
  • Extends shelf life; makes milk safe.

Quick check

  • Name the five major types of microorganisms. Which is not truly a living cell?
  • How does Lactobacillus help make curd?
  • Who discovered penicillin? From which organism was it obtained?
  • Name two diseases caused by each: bacteria, viruses, protozoa.
  • List four food preservation methods and explain the principle behind each.

Open the Practice tab for graded questions on Microorganisms.

4 topics • Notes • Practice • AI explanations available

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